Cool What Is The Most Popular Anime In Japan 2021 References . Home » features » top 20 most popular anime of all time, ranked. Web if you didn’t know, most japanese watch anime late at night. Most Popular Animes In Japan 2021 Detailed List QUESTION JAPAN from questionjapan.com Web according to a survey conducted by the nippon research center in october and november 2020, studio ghibli's totoro was the most popular manga and anime. The vampire cosmonaut ‘s first season premiered on october 4, 2021, and as the series’ title implies, this anime’s story. In my opinion, this ranking is the most accurate but again.